Research

Research & Evidence

Scaling prevention, building evidence, and translating science into policy for better brain health across the UK.

Our Research Approach

The UK Brain Council takes a collaborative, interdisciplinary approach to brain health research. We work across neurology, psychiatry, and public health — recognising that these systems must be integrated rather than siloed to address the full spectrum of brain conditions.

Our research priorities are shaped by the science of prevention and by the experiences of people living with brain conditions. We believe research must be both rigorous and relevant, translating into practical improvements for individuals, communities, and systems.

Cross-disciplinary Focus

We bring together expertise across neurology, psychiatry, and public health to develop integrated approaches that address brain health in its full complexity.

Our Priorities

Research Priority Areas

Life-Course Risk Reduction

Addressing modifiable risk factors across the lifespan — including hypertension, diabetes, and social isolation — that are known to increase the risk of dementia and other brain conditions.

System Integration

Breaking down barriers between neurology, psychiatry, and public health systems to create more coherent, person-centred care and prevention pathways.

Community-Centred Approaches

Developing and evaluating equitable, community-centred interventions that meet people where they are and address the social determinants of brain health.

Brain Capital Metrics

Developing and applying brain capital frameworks in workplace settings, measuring the economic value of brain health investment and making the case for employers and governments to act.

Key Risk Factors

Modifiable Risk Factors We Address

Up to 40% of dementia cases could be prevented or delayed by addressing these known risk factors throughout life.

Hypertension

High blood pressure is one of the most significant modifiable risk factors for stroke and vascular dementia.

Diabetes

Type 2 diabetes is associated with increased risk of cognitive decline and dementia, with prevention and management being key.

Social Isolation

Loneliness and social isolation are significant risk factors for cognitive decline, depression, and dementia in later life.

Physical Inactivity

Regular physical activity is protective for brain health at all ages, reducing risk of stroke, dementia, and depression.

Sleep Disorders

Poor sleep quality and sleep disorders are linked to increased amyloid accumulation and heightened dementia risk.

Head Injury

Traumatic brain injury — including from sport — increases the long-term risk of neurological conditions including CTE and dementia.

Collaborate With Us

Are you a researcher, academic institution, or clinical partner? We welcome collaboration across all areas of brain health research.

Get in Touch